The islands and moorings of southern Messenia constitute the strategic node of the sea routes between the Ionian and Aegean seas. This was the coast tract to be protected by all thalassocracies that patrolled the sea-lanes between East and West Mediterranean. But it was only during the nearly three centuries of Venetian government (1207-1500) that these coastal and island settlements experienced a peak of development. Today they provide scholars and higher education programs with a documentation that is excellent in terms of both quantity and quality, giving us written, architectural and archaeological evidence on the Venetian Stato da Mare. This research was conducted by Andrea Nanetti between 1993 and 2009 in collaboration with the DISMEC of the University of Bologna, the State Archive of Venice and the 26th Ephoreia of Byzantine Antiquities of the Greek Ministry of Culture.